The key ingredients found in MetaboUP PLUS are proven to result in increased weight loss.

Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-hour energy expenditure and fat oxidation in humans

Abdul G. Dulloo, Claudette Duret, Dorothe Rohrer, Lucien Girardier, Nouri Mensi, Marc Fathi, Philippe Chantre, and Jacques Vandermander

Participant levels were monitored over the course of 24 hours in which, on three separate occasions, subjects were randomly assigned to take green tea extract, caffeine, and placebo which was ingested at breakfast, lunch and dinner. It was found that green tea has thermogenic properties and promotes fat oxidation beyond that explained by its caffeine content per se. The green tea extract may play a role in the control of body composition via sympathetic activation of thermogenesis, fat oxidation, or both.

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Changes in caffeine intake and long-term weight change in men and women

Ester Lopez-Garcia, Rob M. van Dam, Swapnil Rajpathak, Walter C. Willett, JoAnn E. Manson, and Frank B Hu

Weight gain is a major determinant of diabetes, and it is possible that a beneficial effect of caffeine on weight might contribute to the inverse association between coffee and diabetes. In this large longitudinal study, an increase in caffeine intake was associated with slightly smaller weight gains in men and women. It has been reported that caffeine stimulates fat utilization in muscle tissue during exercise

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Caffeine and coffee: their influence on metabolic rate and substrate utilization in normal weight and obese individuals

K. J. Acheson, Ph.D., B. Zahorska-Markiewicz, M.D., Ph. Pittet, Ph.D., K. Anantharaman, Ph.D., and E. Jacquier, M.D.

A series of four trials was carried out to investigate the effects of caffeine and coffee on the metabolic rate and substrate utilizatio in normail weight and obese individuals. The thermic effect of the meal was significantly greater after coffee than after decaffeinated coffee and again fat oxidation was significantly greater after coffee. Caffeine/coffee stimulates the metabolic rate in both control and obese individuals; however, this is accompanied by greater oxidation of fat in normal weigh subjects.

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